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FDA approved Arikayce (amikacin liposomal inhalation suspension) recently for patients with Mycobacterium-avium complex infections, not responding to conventional treatment. Boxed Warning Boxed warning with Arikayce includes hypersensitivity pneumonitis, bronchospasm, hemoptysis and exacerbation of the underlying chronic lung disease. Other side effects include dysphonia, cough, ototoxicity, upper airway irritation, fatigue, nausea, diarrhea and myalgias. Safety and …

FDA approved Arikayce for Mycobacterium Avium complex Read More »

Medical inventions have changed the practice of medicine. However, some of them have revolutionized it. For centuries medical practice was based on theories. Most of the researches took place in the last one or two centuries. With the new advances, medical knowledge almost doubles every one to two days. While people are focusing on the …

Six medical inventions that revolutionized medicine!! Read More »

Fatty liver or Non-alcoholic fatty liver disease (NAFLD) refers to fatty accumulation within the liver. When fat accumulation progresses, an inflammatory process is initiated within the liver parenchyma. This is marked by an increase in liver enzymes and called nonalcoholic steatohepatitis. Nonalcoholic steatohepatitis (NASH) may progress to a stage of cirrhosis and Fibrosis in a …

NAFLD (Fatty liver) – Associated with liver cancer! Read More »

The incidence of a serious genital infection, the Fournier’s gangrene, has been noted to rise with the use of SGLT2 inhibitors. This has prompted the FDA to add an alert with its use. SGLT2 inhibitors include dapagliflozin, canagliflozin, empagliflozin, and ertugliflozin. These drugs have recently been marketed for the treatment of type 2 diabetes patients. …

Severe genital infection with the use of SGLT2 inhibitors! Read More »

Low dose aspirin is widely used in the primary and secondary prevention of vascular diseases. However, weight-based dosing of aspirin is probably more effective in the prevention of cardiovascular diseases, especially in obese patients weighing more than 70 kgs. Aspirin (chemical name Acetyl-salicylic acid) is a drug used in the treatment of pain, fever, inflammatory …

Aspirin for primary prevention of vascular events Read More »

World Hepatitis Day – 28 July 2018 World hepatitis day Theme 2018: Test and Treat Hepatitis Hepatitis is an inflammation of the liver. Various pathologic causes are to be blamed but viral hepatitis B and C are major health challenges, affecting 325 million people globally.  They are root causes of liver cancer, leading to 1.34 …

World Hepatitis Day – “Test and Treat Hepatitis” Read More »

“Bariatric surgery isn’t going to make you lose weight; its a tool to help you lose weight. Half of it is the surgery, and half of it is you eating what you are supposed to eat and exercise.” Ashley Nell Tipton What is Obesity Overweight and obesity are defined as abnormal or excessive fat accumulation …

Bariatric surgery – The Only Effective Treatment For Obesity Read More »