Hematology

hereditary spherocytosis

Hereditary Spherocytosis – inheritance, symptoms and treatment

Hereditary spherocytosis is a familial hemolytic disorder with variable clinical features. It is the most common congenital hemolytic disorder due to a defect in the red cell membrane. Hereditary spherocytosis Inheritance: Any of the Six genes that code for proteins responsible for maintaining the membrane skeleton may be defective. Spectrin deficiency leads to loss of …

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